张德禄

发布时间:2019.05.24 17:01

  

  姓名:张德禄    

  性别:    

  出生年月: 19631 

  学位:博士    

  职称:副教授

  Emaildeluzh@163.com     

 

教育经历: 

  2005.9-2009.6 中国科学院水生生研究所 博士 

1995.9-1998.12 甘肃农业大学动物医学院  硕士 

1982.9-1986.6 西北师范大学生物系  本科

 

工作经历: 

  20146-至今 威尼斯wnsr9778 威尼斯wnsr9778 副教授 

  20056-20145 威尼斯wnsr9778 理学院 副教授 

  19923-19941 北京大学基础医学院 进修学习 

  19867-20056 西北师范大学 生命科学学院 助教,讲师,副教授 

 

研究领域: 

主要从事动物结构与功能关系及其机理研究。主要研究方向包括:

(1) 动物生理机能与发育调控研究:研究动物生理机能与发育的神经与内分泌调控,机体微循环与微环境的调控机理。(2) 动物药理毒理机制研究:研究动物行为、动物脏器的生理生化、细胞与分子水平对药物和毒物的响应、代谢以及解毒机制,为药物作用与代谢机制,安全评价提供实验依据。(3)药用动物与新药研发:针对特殊疾病,研究开发药用动物新资源和新技术。(4)动物对环境变化的响应机理:研究动物机体环境变化对动物影响的生理机制。(5)新能源生物培养与研发:培育和研发新的能源生物。 

 

教学. 科研概况: 

  

教学概况:主要承担生物科学、生物技术、生物制药等专业的《动物生物学及生理学》、 《动物生物学及生理学实验》、 《发育生物学》、 《组织学》.和《保健生物学》等课程的教学工作。参编十一五规划教材《人体解剖生理学》和《人体组织解剖学》教材2部。获得2011校师德先进个人1次,校优秀实习指导教师2次、学院先进个人2次、2014-2016院聘期考核优秀1次、获得学院教学类省级优秀论文奖1次、指导的硕士研究生获得国家奖学金1次、指导的本科生获得湖北省动物学实验机能大赛单项奖省级二等奖1次。指导本科毕业论文获省级优秀学士学位论文奖6次、提名奖3次,指导本科生完成大学生自主创新项目研究2项。  

 

科研概况:主要从事动物结构与功能的关系与机理、动物药理与毒理机制、 动物新药研发等研究。主持和参与国家863项目、国家重大专项、国家973项目、 国家自然基金、省科技攻关、省青年基金、和企业合作项目等10项。相关研究在《Aquatic toxicology》、《Environmental toxicology》、《Ecotoxicology and Environmental Safety》、《中国科学》、《科学通报》、《解剖学报》、《畜牧兽医学报》、《湖泊科学》、《水生生物学报》、《兰州大学学报(自然版)》、《动物学杂志》、《西北师范大学学报》 等相关刊物上发表论文80余篇。获省高校科技进步123等奖3项。 

 

主持和参与的科研项目: 

1. 2013-2016,主持完成国家高技术研究发展计划(863计划):利用沙漠产油微藻开发藻渣为高蛋白精细饲料的技术研究。No.(2013AA065804-03)  

2. 2009-2012,主持完成国家重大专项:我国湖泊营养盐生态分区的指标体系研究。No. 2009ZX07106-001

3. 2008-2011,主持完成国家重大专项:经济高效氮磷去除机制的研究与示范,No. 2008ZX07103-004

4. 2013-2016,参与完成国家高技术研究发展计划(863计划):利用沙漠环境培养微藻制备生物柴油关键技术技术研究。No.2013AA065804

5. 2009-2012,参与完成国家重大专项:我国湖泊营养物基准和富营养化控制标准研究。No. 2009ZX07106

6. 2008-2011,参与完成国家重大专项:湖泊直立堤岸基底改善与湖滨带生态修复技术。No. 2008ZX07103-004

7. 2004-2006,参与完成国家基金面上项目:中国西北地区土壤蓝藻的分类及物种多样性研究。 No.30370122

8. 2002-2004,参与完成国家基金面上项目:西北地区优良固土藻种的筛选。No.30170022

9. 2002-2004,参与完成省中青年基金面上项目:河西戈壁土表结皮形成机理研究,No. YS-011-A25-026

10. 2000-2002,主持完成学校中青年基金项目:七彩山鸡生殖系统的血液供应研究。NWNU-2000-02

11. 1998-2000,参与完成省科委攻关资助项目:雉鸡人工繁殖技术的研究。No.G4941-1-74 

12. 1996-1998,参与国家自然基金面上项目:双峰驼肾单位的体视学研究, No.39500109

13. 1994-1997,参与完成国家自然科学基金面上项目:支配母鸡生殖系统神经元的位置和性质,No. 39200091

 

代表性论文与专利:

(1) Zhang Delu, Liu Siyi, Zhang Jing., Zhang Jiankun, Hu Chunxiang, Liu Yongding. In vivo effects of Aphanizomenon flos-aquae DC-1 aphantoxins on gas exchange and ion equilibrium in the zebrafish gill.Aquatic Toxicology2016, 177, 484–493. (SCIIF=3.557,中科院1)

(2) Zhang Delu, Liu Siyi, Zhang Jing., Zhang Jiankun, Hu Chunxiang, Liu Yongding. Respiratory toxicity of cyanobacterial aphantoxins from Aphanizomenon flos-aquae DC-1 in the zebrafish gill. Aquatic Toxicology, 2016, 176 106–115. (SCIIF=3.557中科院1)

(3) Zhang Delu, Liu Siyi, Zhang Jing., Hu Chunxiang, Li Dunhai, Liu Yongding. Antioxidative responses in zebrafish liver exposed to sublethal doses Aphanizomenon flos-aquae DC-1 aphantoxins. Ecotoxicology and Environmental Safety, 2015, 113: 525-532. (SCI, IF=3.13, 中科院3)

(4) Zhang Delu, Zhang Jing, Hu Chunxiang, Wang Gaohong, Li Dunhai, Liu Yongding. Morphological alterations and acetylcholinesterase and monoamine -oxidase inhibition in liver of zebrafish exposed to Aphanizomenonflos- aquae DC-1 aphantoxins. Aquatic Toxicology 2014,157: 215–224. (SCIIF=3.557中科院1)

(5) Zhang Delu, Hu Chunxiang, Wang Gaohong, Li, Dunhai Li Genbao, Liu Yongding. Zebrafish neurotoxicity from Aphantoxins-cyanobacterial paralytic shellfish poisons (PSPs) from Aphanizomenon flos-aquae DC-1. Environmental Toxicology, 2013, 28(5):239-254. (SCIIF=3.557中科院2)

(6) Zhang Delu, Hu Chuxiang, Li Dunhai, Liu Yongding. Zebrafish locomotor capacity and brain acetylcholinesterase activityis altered by Aphanizomenon flos-aquae DC-1 aphantoxins. Aquatic Toxicology 2013,138: 139– 149. (SCIIF=3.557中科院1)

(7) Zhang Delu , Hu Chunxiang, Li Dunhai, Liu Yongding. Lipid peroxidation and antioxidant responses in zebrafish braininduced by Aphanizomenon flos-aquae DC-1 aphantoxins. Aquatic Toxicology, 2013, 144 : 250–256. (SCI,IF=3.5571)

(8) 张德禄,胡春香,王高鸿,李敦海,李根保,,沈银武,刘永定. 斑马鱼脑细胞凋亡基因对束丝藻毒素致毒的响应.水生生物学报, 2011, 35(2): 238-245. (CSCD)

(9) 张德禄,刘永定,胡春香 基于营养盐的中国湖泊生态分区框架与指标体系初探. 湖泊科学,2011, 23(6)821-827. (CSCD)

(10) 张德禄,杜庆才,彭亮,延庆云,刘永定,胡春香. 硝基芳香烃污染物对水生态系统的毒理学研究述评.西北师范大学学报,2007,43(5)98-101.(CSCD)

(11) 张德禄, 崔燕,胡春香,刘永定.母鸡输卵管子宫部初级感觉神经元的CB-HRP定位. 畜牧兽医学报,200637(12):1360-1363. (CSCD)

(12) 张德禄,马正学,马尚胜. 石鸡胃的血液供应  西北师范大学学报(自然版)200339(4):66-69. (CSCD)

(13) 张德禄,崔燕  支配鸡输卵管子宫部交感节后神经元的逆行追踪研究  解剖学报, 200132(1):13-16.  (CSCD)

(14) 张德禄,俞诗源,胡春香 一雄性灰鹤胃的血液供应研究  动物学杂志 200237(5):32-36.  (CSCD)  

(15) 张德禄,俞诗源,刘世倩,胡春香 红腹锦鸡肝脏的显微结构观察  西北师范大学学报(自然版),200238(2):61-63. (CSCD)

(16) 张德禄 刘左军 环颈雉胃的血供  动物学杂志200136(2):11-15. (CSCD)  

(17) 张德禄,胡春香,俞诗源  荒漠沙蜥肺动脉分布和毛细血管超微构筑  兰州大学学报(自然版)200238(4):90-94. (CSCD)  

(18) 张德禄,崔燕  母鸡输卵管子宫部副交感节后神经元位置的逆行追踪研究  畜牧兽医学报 2002 33(3):250-254. (CSCD)  

(19) 张德禄 刘左军  环颈雉食管和器官的血液供应研究  兰州大学学报(自然版)2002 38(1):90-95.(CSCD)  

(20) 张德禄,胡云生,马正学. 七彩山鸡胃的动脉和静脉的解剖学观察  西北师范大学学报(自然版)200137(1):67-72.(CSCD    

(21) 张德禄,俞诗源,程晓. 花背蟾蜍胃肠的血供研究   西北师范大学学报(自然版)200137(4):69-72. (1

(22) 张德禄,俞诗源. 3只红腹锦鸡食管和大肠的显微结构观察  西北师范大学学报(自然版)200036(4):69-72.(CSCD)  

(23) 张德禄,俞诗源,张育康.  3只红腹锦鸡小肠的显微结构观察  西北师范大学学报(自然版),200036(3):63-66.(CSCD) 

(24) 张德禄,俞诗源. 红腹锦鸡胃的血供  西北师范大学学报(自然版)200036(2):68-61.(CSCD)

(25) Yue Tao, Zhang Delu, Hu Chunxiang. Comparative studies on phosphate utilization of two bloom-forming Microcystis sp. (Cyanobacteria) isolated from Lake Taihu (China). Journal of Applied Phycology. 2014, 26:333-339. (SCIIF=2.492,中科院3)

(26) Wu Li, Lan Shubin, Zhang Delu, Hu Chunxiang. Recovery of chlorophyll fluorescence and CO2 exchange in lichen soil crusts after rehydration. European Journal of Soil Biology, 2013, 55: 77-82. (SCIIF=2.445, 中科院3)

(27) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Assessing level of development and successional stages in biological soil crusts with biological indicators. Microbial Ecology, 2013, 66(2):394-403. (SCIIF=3.63,中科院1)

(28) Wu Li, Lan Shubin, Zhang Delu, Hu Chunxiang. Functional reactivation of photosystem II in lichen soil crusts after long-term desiccation. Plant and Soil, 2013, 369 (1): 177-186. (SCIIF=3.235, 中科院2)

(29) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Composition of photosynthetic organisms and diurnal changes of photosynthetic efficiency in algae and moss crusts. Plant and Soil, 2012, 351(1): 325-336. (SCIIF=3.235, 中科院2)

(30) Lan Shubin,Wu Li,Zhang Delu,Hu Chunxiang.Desiccation provides photosynthetic protection for crust cyanobacteria Microcoleus vaginatus from high temperature. Physiologia Plantrum,2014,152:345-354. (SCIIF=3.33,中科院2)

(31) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Successional stages of biological soil crusts and their microstructure variability in Shapotou region (China). Environ. Earth Sci., 2012, 65: 77-88. (SCIIF=1.57, 中科院3)

(32) Wu Li, Lan Shubin, Zhang Delu, Hu Chunxiang. Small-Scale Vertical Distribution of Algae and Structure of Lichen Soil Crusts. Microb Ecol, 2011, 62:715–724. (SCIIF=3.63, 中科院1)

(33) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Desiccation provides photosynthetic protection for crust cyanobacteria Microcoleus vaginatus from high temperature. Physiologia Plantrum2014,152:345–354. (SCI,IF=3.33,中科院2)

(34) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang, Liu Yongding. Effects of drought and salt stress on man-made cyanobacterial crusts. European journal of soil biology, 2010,46381-386.(SCIIF=2.445, 中科院3)

(35) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Effects of light and temperature on open cultivation of desert cyanobacterium Microcoleus vaginatus. Bioresource Technology 182 (2015) 144–150. (SCIIF=4.917, 中科院1)

(36) Lan Shubin, Wu Li, Zhang Delu, Hu Chunxiang. Analysis of environmental factors determining development and succession in biological soil crusts. Science of the Total Environment, 2015, 538:492–499. (SCIIF=4.9, 中科院1)

(37) Shubin Lan,Li Wu,Delu Zhang,Chunxiang Hu,Yongding Liu Ethanol outperforms multiple solvents in the extraction of chlorophyll-a from biological soil crusts. Soil Biology & Biochemistry,2011,43:857-861. (SCI,IF=4.857,中科院1)

(38) 岳涛,张德禄, 胡春香. 太湖三种优势微囊藻对不同形态磷的吸收利用. 湖泊科学,201426( 3) : 379-384.(CSCD)

24) 兰书斌,吴丽,张德禄 胡春香 南四湖沼泽化成因及其驱动因素分析. 湖泊科学,2011,23(4)555-560 (CSCD) 

(39) Shubin Lan, Li Wu, Haijian Yang, Delu Zhang, Chunxiang Hu. A new biofilm based microalgal cultivation approach on shifting sand surface for desert cyanobacterium Microcoleus vaginatus. Bioresource Technology2017,238:602-608. (SCIIF=4.917, 中科院1)

(40) Lv Ying, Xue Xing, Tao Ling, Zhang Delu, Hu Chunxiang., Ren Jun. Extracellular Polymeric Substances of Aphanizomenon flos-aquae (EPS-A) Induced Apoptosis in Astrocytes of Zebrafish. Bull Environ Contam Toxicol., 2016, 96(3):320-325. (SCIIF=1.412, 中科院4)

(42) Xia Ling, Zhou Xuping, Ge Hongmei, Zhang Delu, Hu Chunxiang. Photoautotrophic outdoor two-stage cultivation for oleaginous microalgae Scenedesmus obtusus XJ-15. Bioresource Technology, 2013, 144: 261-267. (SCIIF=4.917, 中科院1)

(42) Zhou Xuping, Ge Hongmei,Xia Ling, Zhang Delu, Hu Chunxiang. Feasibility of biodiesel production by microalgae Chlorella sp.(FACHB-1748) under outdoor conditions. Bioresource Technology,2013,138,131-135.(SCI,IF=4.917,中科院1)

(43) Zhou Xuping, Ge Hongmei, Xia Ling, Zhang Delu, Hu Chunxiang. Evaluation of oil-producing algae as potential biodiesel feedstock. Bioresource Technology, 2013, 134: 24-29. (SCIIF=4.917, 中科院1)

(44) Ge Hongmei, Xia Ling, Zhou Xuping, Zhang Delu, Hu Chunxiang. Effects of light intensity on component and topographical structure of extracellular polysaccharide from the cyanobacteria Nostoc sp. The Journal of Microbiology, 2014, 52(2): 179-183. (SCIIF=2.146, 中科院3)

(45) Wu Li, Zhang Gaoke, Lan Shubin, Zhang Delu, Hu Chunxiang. Microstructures and photosynthetic diurnal changes in the different types of lichen soil crusts. European Journal of Soil Biology, 2013, 59: 48-53. (SCIIF=2.445, 中科院3)

(46) Wu Li, Zhang Gaoke, Lan Shubin, Zhang Delu, Hu Chunxiang. Longitudinal photosynthetic gradient in crust lichens’ thalli. Microbial Ecology, 2014, 67:888–896. (SCIIF=3.63, 中科院1)

(47) Xia Ling, Rong Junfeng, Yang Haijian He Qiaoning, Zhang Delu, Hu Chunxiang. NaCl as an effective inducer for lipid accumulation in freshwater microalgae Desmodesmus abundans. Bioresource Technology, 2014, 161:402-409. (SCIIF=4.917, 中科院1)

(48) Lan Shubin, Zhang Qingyi, Wu Li. Liu Yongding, Zhang Delu, Hu Chunxiang. Artificially accelerating the reversal of desertification:cyanobacterial inoculation facilitates the succession of vegetation communities. Environmental Science & Technology, 2014, 48, 307-315. (SCIIF=5.481, 中科院1)

(49) Lv YingXue Xing, Tao Ling, Zhang Delu, Hu Chunxiang. Effect of extracellular polymeric substances from aphanizomenon flos-aquae (EPS-A) on human epidermoid carcinoma (A431 cells).Fresenius Environmental Bulletin201524(10A):3307-3314. (SCIIF=0.372, 中科院4)

(50) Lan Shubin, Ouyang Hailong, Wu Li, Zhang Delu, Hu Chunxiang Biological soil crust community types differ in photosynthetic pigment composition, fluorescence and carbon fixation in Shapotou region of China. Applied Soil Ecology, 2017111:9-16. (SCIIF=2.78,中科院3)

(51) Lan Shubin, Hu Chunxiang, Rao Benqiang, Wu Li, Zhang Delu, LiuYongding. Non-rainlfall water sources in the topsoil and their changes during formation of man-made algal crusts at the eastern edge of Qubqi Desert,Inner Mongolia. Science China:Life Sciences, 2010, 53(9):1135-1141. (SCIIF=1.345, 中科院4 

 

著作: 

  1. 高校教材 《人体组织解剖学》,参编,兰州大学出版社,1998.

  2. 十一五规划教材 《人体解剖生理学》,参编,兰州大学出版社,2007.3 

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