张静丽
姓名:张静丽
性别:女
出生年月:1974年8月
学位:博士
职称:副教授,硕士生导师
Email:junniz@163.com
教育经历:
1993.09-1997.06 武汉化工学院 精细化工系 化学制药专业,学士学位
2002.09-2005.06 华中科技大学 生命科学学院 生物化工专业 硕士学位
2005.09-2011.06 华中科技大学 化学化工学院 材料物理与化学专业 博士学位
研究领域:
研究兴趣:1) 含氟有机化合物的合成;2)金属催化的有机合成方法学研究;3)药物合成及杂环化合物合成;4)聚合物纳米反应器仿酶催化
教学、科研概况:
在校工作期间,认真负责对待教学工作,承担的所有本科教学任务的综合评价结果基本为90分以上,每年的理论及实践课程都能获学校优质优酬奖;经常鼓励本科生到科研实验室进行拓展与锻炼,先后指导多名本科生开展创新研究,效果良好。
主要科研项目和成果:
1、手性糖分子响应性智能表面的设计、制备及识别响应机理研究 4万 威尼斯wnsr9778自主创新基金 2012-2013
2、糖识别手性响应性智能表面的制备及其识别响应机理研究 5万 中国博士后科学基金 2012-2014
3、共轭烯醛的生物催化和仿生催化的不对称反应研究 4万 威尼斯wnsr9778自主创新基金 2014-2015
4、热响应性单链聚合物纳米反应器的制备及其对水相Aldol反应的可控仿生催化研究 25万国家自然科学基金青年基金 2015-2017
代表性论文与专利:
1、 Jingli Zhang, Liran Liu, Junxin Duan, Lianghu Gu, Bifeng Chen, Taolei Sun*, Yuefa Gong*. Stereoselective one-pot sequential dehydrochlorination/trans-hydrofluorination reaction of β-chloro-α,β-unsaturated aldehydes or ketones: facile access to (Z)-β-fluoro-β-arylenals/β-fluoro-β-arylenones. Adv. Synth. Catal. 2017, 359(24):4348-4358. (IF : 5.646)
2、王鹏,张静丽*,卿光焱. 有机催化的聚合物纳米反应器在仿酶催化中的研究进展. 材料导报 2015, 29(5): 1-12.
3、 Jingli Zhang, Mingxi Zhang, Kangjian Tang, Francis Verpoort, Taolei Sun*, Polymer-based stimuli-responsive recyclable catalytic systems for organic synthesis. Small, 2014, 10(1): 32-46.(IF: 7.823)
4 、Jingli Zhang, Lianghu Gu, Yuefa Gong*, Direct vinylogous aldol reaction triggered by tetrabutylammonium fluoride: a highly regioselective and diastereoselective addition of cyclic β-haloenals to aromatic aldehydes. Synlett, 2012, 3: 468-472. (IF: 2.655)
5、 Jing-Li Zhang, Yue-Fa Gong*, Cross-coupling reactions of two different activated alkenes through tetrabutylammonium fluoride (TBAF) promoted deprotonation/activation strategy: a regioselective construction of quaternary carbon centers. Organic Letters, 2011, 13(2): 176-179.(IF: 6.142)
6 、Lianghu Gu, Yirong Zhou, Jingli Zhang, Yuefa Gong*, A highly chemo- and enantioselective nitroaldol reaction of haloenals: preparation of chiral functionalized allylic alcohols. Tetrahedron: Asymmetry, 2012, 23(2):124-129.(IF: 2.115)
7、 Wen Kong, Xiao Fu, Lei Wang, Ahmad Alhujaily, Jingli Zhang, Fuying Ma, Xiaoyu Zhang, Hongbo Yu*. A novel and efficient fungal delignification strategy based on versatile peroxidase for lignocelluloses bioconversion. Biotechnol Biofuels, 2017, 10: 218-232. (IF: 5.203)
8 、Xianhong Feng, Jingdong Wang, Xiuli Gu, Jingli Zhang, Xiaolin Li, Zhi Tao, Jiebing Chen, Bifeng Chen*. Association of DNMT3B-283T>C polymorphism with risk of lung and gastric cancer: a case-control study and a meta-analysis. Int J Biol Markers. 2017
9 、Jingdong Wang, Chade Li, Fengting Wan, Zhou Li, Jingli Zhang, Jiankun Zhang, Xianhong Feng, Liang Tang, Bifeng Chen*. The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population. Oncotarget, 2017, 8(14): 23470-23478. (IF: 5.168)
10、 Bifeng Chen*, Jingdong Wang, Xiuli Gu, Jingli Zhang, Jiankun Zhang, Xianhong Feng. The DNMT3B-579G>T Polymorphism is significantly associated with the risk of gastric cancer but not lung cancer in Chinese population. Technology in Cancer Research & Treatment. 2017, 16(6): 1259-1265. (IF: 2.204)